This just in before the weekend:

Complete Genomics have published its first few genomes, and despite (somewhat) dodgy statistics on the quality of the assembly they are in business. More here.

Nature paper out on the ‘complete’ epigenome hints that embryonic cells may use different mechanisms for gene regulation than more differentiated cells. Abstract here.

Lastly, Microsoft would like to take a step into the world of bioinformatics. What they really want to is to take a strong tradition for open source and wrap it in proprietary frameworks so we can be even more reliant on Microsoft products. Posted here (Gleen Moodys comment) and here (Microsoft statement).

Tired of clicking your way to the article PDFs you need? Check this out and find out how you can fully automate this process.

Gene set enrichment analysis is a standard method for testing the association between some subset of genes and an expression profile. Several methods have been developed over the past few years, and now a publication is out trying to assess which method / parameters provides the better performance. So take a look: A general modular framework for gene set enrichment analysis